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Posts Tagged ‘Ultrasound’

Radiology: The Basic Modalities
Ultrasound Mammography – Vol. 1, Number 6

Wednesday, October 31st, 2007

How it works. As discussed in a recent issue of The WCC Note (Volume 1, Number 3), an ultrasound machine uses sound waves to differentiate the types of tissues within the breast.  Because of the lack of radiation and its ability to see structures in “real time,” ultrasound is a good tool for the evaluation of the breast in certain situations.

However, ultrasound is not a good test for screening the breasts – that is, if a healthy woman without any symptoms gets an ultrasound scan, it can be extremely difficult to find a small cancer.  In addition, ultrasound is a poor test in patients with very large or dense breasts, because the sound waves cannot pass through the excess fatty tissue.  Breast ultrasound is useful in evaluating masses that have already been seen on a mammogram or felt by a patient.

Evaluating a Known Mass
If a woman feels a lump in her breast but it can’t be seen on a mammogram, or if a mass is seen on a mammogram but it is uncertain whether it is benign or malignant (which is very common), an ultrasound can be done to evaluate it further.  In these situations, the ultrasound operator already knows the location of the mass and can do a dedicated ultrasound examination of that area to characterize it better.  This is useful because an ultrasound can show that a mass is definitely a benign growth, which would prevent the woman form having to get a biopsy.

The most common benign mass that can be confirmed on an ultrasound is a simple cyst – a small collection of fluid (see Figure 1).  Ultrasound is extremely accurate in identifying simple cysts, because it depends on the transmission of sound waves and simple fluid transmits sound waves very well.  As a result, a simple cyst will appear completely black on ultrasound; this black appearance is “anechoic,” meaning that the fluid produces no echoes, or does not make any of the sound waves bounce back, because the sound waves are transmitted through it so easily.

BIOPSIES: ULTRASOUND, STEREOTACTIC, AND MRI

A biopsy is a procedure where a small piece of a mass that is suspected to be cancer is removed from a patient using a needle, so that it can be examined under a microscope to see what it is.  Ultrasound is also very useful in helping physicians find the right place to insert the needle during a biopsy.  Because it is a “real-time” imaging exam, the images seen on the screen show exactly what is happening at the time the transducer is on the patient see Figure 2).  Thus, a physician can watch in real time as the needle goes through the patient’s skin and into a mass, to make sure it is going to the correct place.

Another method used for breast biopsy is stereotactic biopsy, which uses x-ray (or mammogram) guidance instead of ultrasound guidance.  Because x-rays cannot be done as real-time exams, in a stereotactic biopsy the physician (with the help of a computer program) figures out exactly where to place the needle based on x-rays taken prior to the biopsy.  After careful planning, a machine helps the physician place the needle in the center of the mass.  X-rays are taken again aftre the needle is placed, to confirm that it is in the correct position.

As we discussed in the last edition, a newer technique for breast biopsy is MRI-guided biopsy, which is used only for masses that cannot be seen on either a mammogram or ultrasound.

Breast-MRI

Radiology: The Basic Modalities
Ultrasound – Vol. 1, Number 3

Wednesday, October 10th, 2007

How it works. Ultrasound is a sound wave with a frequency higher than the range audible by the human ear.  The frequency used in dagnostic radiology is in the range of approximately 1 to 10 megahertz; audible sound is about 20 hertz to 20 kilohertz.

Ultrasonography has many medical applications in which a machine is used to create these high-frequency sound waves.  The machine has a hand-held wand (or transducer), which is placed directly on the patient’s skin.  The sound waves emanate from the face of the transducer, which is a few inches long, relatively thin, and shaped like an electric shaver.

The sound waves are transmitted through the patient’s body, so the area that is imaged consists of the skin under the transducer and everything below it.  In other words, when you place the transducer on the patient, the image shown on the screen will be a “slice” of the body below the spot where you place it.

How the Images Are Made
Depending on the ability of the tissue to transmit sound, the sound wave will either penetrate through the tissue or bounce back and hit the transducer.  A substance such as water is a very good transmitter of sound; as a result, when ultrasound waves are aimed at water, very little bounces back.  Substances such as fat, air and bone do not transmit sound well, however, so the waves bounce back to the transducer.

The ultrasound machine then records the sound waves that return to the transducer.  It can calculate from where the waves are coming, based on the frequency of the sound.  The machine then creates a grayscale “map” of the information it receives.  Areas from which a lot of sound bounces back appear white (such as fat, bone, or air); areas with not sound return (such as water) appear black.  A liquefied gel is always placed between the transducer and the patient’s skin to eliminate any air between them.

SOME PROS AND CONS OF ULTRASOUND

Advantages

  • Cheap
  • Fast
  • “Real-time” imaging allows examiner to see motion of tissues*
  • No radiation (as a result, used often in children)**
  • Can distinguish simple cysts from masses reliably
  • “Real-time” imaging useful to guide biopsies****
  • Can evaluate blood flow

Disadvantages

  • Quality of images depends on expertise of operator
  • Anatomic detail is poor because of low resolution
  • Cannot evaluate bone, lungs, or bowel***
  • Images are poor in obese patients***
  • Images are poor when air or gas is present
  • Small field of view

* Ultrasound images are extremely easy and fast to create; as a result, ultrasound is a “real-time” exam.  In other words, when the transducer is placed on the skin, the image of the tissues below it appears almost immediately on the ultrasound screen.  This allows the examiner to move the wand back and forth to see the actual movement of tissues in the body as it happens.
** There is absolutely no ionizing radiation associated with ultrasound.  The only documented potential adverse effect is that, when used for long periods of time at high intensities, it can cause slight heating of the tissues.
*** Ultrasound cannot be used to evaluate hard structures, such as bone and metal, or structures with a lot of air, such as the lungs or bowel.  Sound waves cannot transmit through these tissues, so they will bounce right off the surface.  On the ultrasound image, this appears as a rim of white (the surface off which the ultrasound bounced) and then pure blackness behind it (an area that the sound waves cannot reach), an effect termed “shadowing.”  In addition, because fat is a poor transmitter of sound, patients with a lot of subcutaneous fat tissue are difficult to image with ultrasound.
****”Doppler ultrasound” can be used to evaluate flow in blood vessels, as well as blood flow in solid organs or masses.

ULTRASOUND’S MOST COMMON USES

Head and Neck:

  • The brain, in newborn infants (the fontanelle is used as an opening to see through)
  • The thyroid gland

Chest:

  • The motion of the heart (echocardiography) – this can be done through the skin (conventional) or through the esophagus (transesophageal)
  • Masses in the breast previously seen on mammography or felt by patient or doctor

Abdomen/Pelvis:

  • The uterus and ovaries – the transducer can be placed on the skin (transabdominal) or in the vagina (transvaginal)
  • Fetuses – good because there is no radiation and the imager can see motion
  • The solid abdominal organs (liver, spleen, pancreas), for masses or biliary dilation
    (Note: the pancreas is often difficult to see because of overlying bowel gas)
  • The gall bladder, for stones and inflammation
  • The kidneys, for mass or hydronephrosis
  • The appendix, for inflammation (usually in children)
  • The prostate gland (transrectal ultrasound, with the transducer placed in the rectum)

Other Uses:

  • The testicles
  • Lymph nodes
  • Masses anywhere in the body, to determine if they are simple cysts
  • Arteries and veins (to look for thrombosis, atherosclerosis, or aneurysm)
  • To guide biopsies in any of the above places

More Advanced Uses

  • Intravenous ultrasound – to evaluate the inside of blood vessels
  • Ultrasound therapy – powerful ultrasound produces heating, which is often used in physical therapy
  • Focused ultrasound surgery – for treatment of some tumors, such as uterine fibroids